Cheapest one-way flights from Chicago to Rome in April from $303

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rome (FCO) in April 2026 (see full year).

One-Way flights

20 Apr jetBlue
29 Apr Scandinavian Airlines
13 Apr Scandinavian Airlines
24 Apr Scandinavian Airlines
17 Apr Scandinavian Airlines
22 Apr Scandinavian Airlines
26 Apr ITA Airways direct
22 Apr ITA Airways direct
29 Apr ITA Airways direct
19 Apr ITA Airways direct

Also check the deals for return flights from Chicago to Rome in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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