Cheapest one-way flights from Chicago to Rome in May from $365

Best time to book flights for Chicago (ORD) to Rome (FCO) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rome (FCO) in May 2025 (see full year).

One-Way flights

25 May Spirit Airlines
28 May Spirit Airlines
29 May Spirit Airlines
30 May Spirit Airlines
14 May TAP
24 May Spirit Airlines
14 May ITA Airways direct
20 May Frontier Airlines
23 May Frontier Airlines
18 May Lufthansa

Also check the deals for return flights from Chicago to Rome in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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