Cheapest one-way flights from Chicago to Guatemala City in December from $106

AirHint found the following cheapest one-way flights from Chicago (ORD) to Guatemala City (GUA) in December 2025 (see full year).

One-Way flights

31 Dec Spirit Airlines
31 Dec Avianca direct
26 Dec Frontier Airlines
29 Dec Spirit Airlines
27 Dec Frontier Airlines
28 Dec Key Lime Air dba Denver Air Connection
29 Dec United direct
24 Dec Avianca direct
30 Dec United direct
22 Dec Frontier Airlines

Also check the deals for return flights from Chicago to Guatemala City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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