Cheapest one-way flights from Chicago to Istanbul in October from $244

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in October 2025 (see full year).

One-Way flights

08 Oct Spirit Airlines
07 Oct Spirit Airlines
05 Oct Spirit Airlines
01 Oct Frontier Airlines
15 Oct Spirit Airlines
26 Oct Frontier Airlines
03 Oct Frontier Airlines
02 Oct Spirit Airlines
12 Oct TAP
17 Oct Frontier Airlines

Also check the deals for return flights from Chicago to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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