Cheapest one-way flights from Chicago to Istanbul in April from $241

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in April 2026 (see full year).

One-Way flights

08 Apr Icelandair
12 Apr Icelandair
07 Apr Icelandair
20 Apr Icelandair
26 Apr Icelandair
01 Apr Air Serbia
08 Apr Turkish Airlines direct
26 Apr Turkish Airlines direct
12 Apr Turkish Airlines direct
20 Apr Turkish Airlines direct

Also check the deals for return flights from Chicago to Istanbul in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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