Cheapest one-way flights from Chicago to Istanbul in April from $300

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in April 2026 (see full year).

One-Way flights

22 Apr Spirit Airlines
26 Apr Spirit Airlines
20 Apr Spirit Airlines
21 Apr Spirit Airlines
28 Apr Icelandair
30 Apr Spirit Airlines
01 Apr Spirit Airlines
29 Apr LOT
30 Apr Turkish Airlines direct
28 Apr Turkish Airlines direct

Also check the deals for return flights from Chicago to Istanbul in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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