Cheapest one-way flights from Chicago to Istanbul in September from $275

Best time to book flights for Chicago (ORD) to Istanbul (IST) flights at AirHint

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in September 2025 (see full year).

One-Way flights

24 Sep Spirit Airlines
12 Sep Icelandair
01 Sep Icelandair
30 Sep Icelandair
03 Sep Icelandair
02 Sep Icelandair
15 Sep Air Serbia
23 Sep Icelandair
24 Sep Turkish Airlines direct
02 Sep Turkish Airlines direct

Also check the deals for return flights from Chicago to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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