Cheapest one-way flights from Chicago to Madrid in October from $233

AirHint found the following cheapest one-way flights from Chicago (ORD) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

24 Oct Spirit Airlines
26 Oct Spirit Airlines
05 Oct Icelandair
19 Oct Spirit Airlines
23 Oct Icelandair
15 Oct Spirit Airlines
01 Oct Icelandair
09 Oct TAP
21 Oct United
19 Oct British Airways direct

Also check the deals for return flights from Chicago to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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