AirHint found the following cheapest one-way flights from Chicago (ORD) to Madrid (MAD) in December 2025 (see full year).
One-Way flights
| 30 Dec | Icelandair | ||
| 31 Dec | Icelandair | ||
| 28 Dec | Aer Lingus | ||
| 25 Dec | Air Canada | ||
| 30 Dec | Iberia | direct | |
| 28 Dec | Iberia | direct | |
| 24 Dec | Air Canada | ||
| 31 Dec | Iberia | direct | |
| 23 Dec | British Airways | ||
| 25 Dec | Iberia | direct |
Also check the deals for return flights from Chicago to Madrid in December.
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