Cheapest one-way flights from Chicago to Madrid in April from $275

AirHint found the following cheapest one-way flights from Chicago (ORD) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

08 Apr TAP
05 Apr TAP
29 Apr TAP
07 Apr jetBlue
06 Apr ITA Airways
29 Apr Finnair direct
05 Apr British Airways direct
07 Apr American Airlines direct
08 Apr American Airlines direct
06 Apr American Airlines direct

Also check the deals for return flights from Chicago to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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