Cheapest one-way flights from Chicago to Rio Negro in December from $109

AirHint found the following cheapest one-way flights from Chicago (ORD) to Rio Negro (MDE) in December 2025 (see full year).

One-Way flights

06 Dec Spirit Airlines
30 Dec Spirit Airlines
07 Dec Frontier Airlines
10 Dec Spirit Airlines
01 Dec Copa
04 Dec Copa
09 Dec Spirit Airlines
23 Dec Spirit Airlines
16 Dec Spirit Airlines
27 Dec United

Also check the deals for return flights from Chicago to Rio Negro in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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