AirHint found the following cheapest one-way flights from Portland (PDX) to Istanbul (IST) in December 2025 (see full year).
One-Way flights
| 09 Dec | Icelandair | ||
| 01 Dec | Icelandair | ||
| 02 Dec | Icelandair | ||
| 16 Dec | Icelandair | ||
| 25 Dec | Air Canada | ||
| 14 Dec | Frontier Airlines |
Also check the deals for return flights from Portland to Istanbul in December.
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