AirHint found the following cheapest one-way flights from Puerto Maldonado (PEM) to Cuzco (CUZ) in October 2025 (see full year).

One-Way flights

04 Oct	Sky Airline	direct
23 Oct	Sky Airline	direct
05 Oct	Sky Airline	direct
28 Oct	Sky Airline	direct
07 Oct	Sky Airline	direct
11 Oct	Sky Airline	direct
19 Oct	Sky Airline	direct
09 Oct	Sky Airline	direct
14 Oct	Sky Airline	direct
16 Oct	Sky Airline	direct

Also check the deals for return flights from Puerto Maldonado to Cuzco in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Puerto Maldonado to Cuzco in October from $19

One-Way flights