AirHint found the following cheapest one-way flights from Puerto Maldonado (PEM) to Cuzco (CUZ) in September 2025 (see full year).

One-Way flights

25 Sep	Sky Airline	direct
19 Sep	Sky Airline	direct
28 Sep	Sky Airline	direct
15 Sep	Sky Airline	direct
13 Sep	Sky Airline	direct
07 Sep	Sky Airline	direct
14 Sep	Sky Airline	direct
09 Sep	Sky Airline	direct
01 Sep	Sky Airline	direct
17 Sep	Sky Airline	direct

Also check the deals for return flights from Puerto Maldonado to Cuzco in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Puerto Maldonado to Cuzco in September from $19

One-Way flights