Cheapest one-way flights from Palermo to Prague in December from $46

AirHint found the following cheapest one-way flights from Palermo (PMO) to Prague (PRG) in December 2025 (see full year).

One-Way flights

20 Dec Ryanair
17 Dec Ryanair
15 Dec Ryanair
21 Dec easyJet
16 Dec Ryanair
23 Dec Ryanair
18 Dec Ryanair
22 Dec Volotea
19 Dec Ryanair
27 Dec Ryanair

Also check the deals for return flights from Palermo to Prague in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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