AirHint found the following cheapest one-way flights from Prague (PRG) to Mexico City (MEX) in December 2025 (see full year).
One-Way flights
| 03 Dec | Transavia France | ||
| 28 Dec | Ryanair | ||
| 17 Dec | Smart Wings | ||
| 11 Dec | Condor | ||
| 12 Dec | British Airways |
Also check the deals for return flights from Prague to Mexico City in December.
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