Cheapest one-way flights from Raleigh-durham to Guayaquil in September from $150

AirHint found the following cheapest one-way flights from Raleigh-durham (RDU) to Guayaquil (GYE) in September 2025 (see full year).

One-Way flights

17 Sep Frontier Airlines
06 Sep Frontier Airlines
15 Sep LATAM Airlines Group

Also check the deals for return flights from Raleigh-durham to Guayaquil in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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