AirHint found the following cheapest one-way flights from Raleigh-durham (RDU) to Rio Negro (MDE) in October 2025 (see full year).
One-Way flights
| 27 Oct | Spirit Airlines | ||
| 03 Oct | Spirit Airlines | ||
| 26 Oct | Spirit Airlines | ||
| 30 Oct | Spirit Airlines | ||
| 12 Oct | jetBlue | ||
| 02 Oct | United | ||
| 23 Oct | Spirit Airlines |
Also check the deals for return flights from Raleigh-durham to Rio Negro in October.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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