Cheapest one-way flights from Raleigh-durham to Rio Negro in April from $129

AirHint found the following cheapest one-way flights from Raleigh-durham (RDU) to Rio Negro (MDE) in April 2026 (see full year).

One-Way flights

12 Apr Copa
18 Apr Spirit Airlines
27 Apr Spirit Airlines
06 Apr Spirit Airlines
09 Apr Spirit Airlines
30 Apr Spirit Airlines
24 Apr Spirit Airlines
03 Apr Spirit Airlines

Also check the deals for return flights from Raleigh-durham to Rio Negro in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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