AirHint found the following cheapest one-way flights from Rome (ROM) to Osaka (KIX) in September 2025 (see full year).

One-Way flights

10 Sep	Sichuan Airlines
19 Sep	Sichuan Airlines
13 Sep	Sichuan Airlines
12 Sep	Sichuan Airlines
03 Sep	Sichuan Airlines
04 Sep	Sichuan Airlines
01 Sep	Wizz Air
07 Sep	Sichuan Airlines
06 Sep	Sichuan Airlines
22 Sep	Wizz Air

Also check the deals for return flights from Rome to Osaka in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Rome to Osaka in September from $410

One-Way flights