Cheapest one-way flights from Rome to Santander in December from $54

AirHint found the following cheapest one-way flights from Rome (ROM) to Santander (SDR) in December 2025 (see full year).

One-Way flights

04 Dec Vueling Airlines
12 Dec Vueling Airlines
17 Dec Vueling Airlines
03 Dec Vueling Airlines
14 Dec Vueling Airlines
05 Dec Vueling Airlines
09 Dec Vueling Airlines
07 Dec Vueling Airlines
18 Dec Vueling Airlines
28 Dec Wizz Air Malta

Also check the deals for return flights from Rome to Santander in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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