Cheapest one-way flights from San Diego to Milano in December from $322

AirHint found the following cheapest one-way flights from San Diego (SAN) to Milano (MXP) in December 2025 (see full year).

One-Way flights

01 Dec Frontier Airlines
04 Dec Frontier Airlines
02 Dec Frontier Airlines
11 Dec Lufthansa
03 Dec WestJet
31 Dec Lufthansa
29 Dec United
23 Dec Frontier Airlines
12 Dec Air Canada
21 Dec Porter Airlines (Canada) Ltd

Also check the deals for return flights from San Diego to Milano in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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