Cheapest one-way flights from San Diego to Panama City in December from $174

AirHint found the following cheapest one-way flights from San Diego (SAN) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

01 Dec Copa direct
03 Dec Copa direct
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08 Dec Copa direct
09 Dec Copa direct
10 Dec Copa direct
12 Dec Copa direct
14 Dec Copa direct
15 Dec Copa direct
16 Dec Copa direct

Also check the deals for return flights from San Diego to Panama City in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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