AirHint found the following cheapest one-way flights from Santiago (SCL) to Barcelona (BCN) in October 2025 (see full year).

One-Way flights

25 Oct	LEVEL	direct
21 Oct	LEVEL	direct
23 Oct	LEVEL	direct
11 Oct	LEVEL	direct
30 Oct	Iberia	direct
27 Oct	Iberia	direct
28 Oct	Iberia	direct
19 Oct	LATAM Airlines Group
07 Oct	Avianca
15 Oct	Avianca

Also check the deals for return flights from Santiago to Barcelona in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Santiago to Barcelona in October from $357

One-Way flights