AirHint found the following cheapest one-way flights from Santiago (SCL) to Cali (CLO) in October 2025 (see full year).

One-Way flights

08 Oct	JetSmart
20 Oct	LATAM Airlines Group
20 Oct	JetSmart	direct
24 Oct	JetSmart
05 Oct	LATAM Airlines Group
19 Oct	JetSmart	direct
08 Oct	JetSmart	direct
03 Oct	JetSmart	direct
26 Oct	JetSmart	direct
01 Oct	JetSmart	direct

Also check the deals for return flights from Santiago to Cali in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Santiago to Cali in October from $144

One-Way flights