Cheapest one-way flights from Santiago to Johannesburg in December from $656

AirHint found the following cheapest one-way flights from Santiago (SCL) to Johannesburg (JNB) in December 2025 (see full year).

One-Way flights

07 Dec LATAM Airlines Group
01 Dec Sky Airline
22 Dec LATAM Airlines Group
24 Dec LATAM Airlines Group
13 Dec LATAM Airlines Group
17 Dec LATAM Airlines Group

Also check the deals for return flights from Santiago to Johannesburg in December.

Powered by

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Johannesburg

Cheap car rent in Johannesburg

Feel free to contact us with any feedback or request another flight research.