Cheapest one-way flights from Santiago to Lisbon in December from $396

AirHint found the following cheapest one-way flights from Santiago (SCL) to Lisbon (LIS) in December 2025 (see full year).

One-Way flights

02 Dec Iberia For Level
07 Dec LATAM Airlines Group
01 Dec LATAM Airlines Group
11 Dec LATAM Airlines Group
10 Dec LATAM Airlines Group
13 Dec LATAM Airlines Group
21 Dec Iberia
22 Dec Iberia
18 Dec Avianca
17 Dec Avianca

Also check the deals for return flights from Santiago to Lisbon in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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