Cheapest one-way flights from Santiago to La Serena in November from $24

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in November 2025 (see full year).

One-Way flights

08 Nov Sky Airline direct
27 Nov Sky Airline direct
04 Nov JetSmart direct
06 Nov Sky Airline direct

Also check the deals for return flights from Santiago to La Serena in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in La Serena

Cheap car rent in La Serena

Feel free to contact us with any feedback or request another flight research.