Cheapest one-way flights from Santiago to La Serena in April from $24

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in April 2026 (see full year).

One-Way flights

07 Apr Sky Airline direct
05 Apr JetSmart direct
04 Apr JetSmart direct
13 Apr JetSmart direct
11 Apr JetSmart direct

Also check the deals for return flights from Santiago to La Serena in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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