Cheapest one-way flights from Santiago to La Serena in May from $21

Best time to book flights for Santiago (SCL) to La Serena (LSC) flights at AirHint

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in May 2025 (see full year).

One-Way flights

20 May Sky Airline direct
29 May JetSmart direct
31 May JetSmart direct
18 May JetSmart direct
25 May JetSmart direct
19 May Sky Airline direct
23 May Sky Airline direct
17 May JetSmart direct
30 May Sky Airline direct
13 May Sky Airline direct

Also check the deals for return flights from Santiago to La Serena in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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