Cheapest one-way flights from Santiago to La Serena in September from $26

AirHint found the following cheapest one-way flights from Santiago (SCL) to La Serena (LSC) in September 2025 (see full year).

One-Way flights

15 Sep Sky Airline direct
14 Sep Sky Airline direct
20 Sep Sky Airline direct
26 Sep JetSmart direct
07 Sep JetSmart direct
16 Sep LATAM Airlines Group direct
28 Sep Sky Airline direct
25 Sep JetSmart direct
12 Sep LATAM Airlines Group direct
13 Sep JetSmart direct

Also check the deals for return flights from Santiago to La Serena in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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