Cheapest one-way flights from Santiago to Madrid in December from $657

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

15 Dec Iberia direct
18 Dec Iberia direct
16 Dec Iberia direct
17 Dec Iberia direct
19 Dec Iberia direct
24 Dec Avianca
25 Dec Avianca
22 Dec Hahn Air Technologies
27 Dec Hahn Air Technologies
21 Dec Avianca

Also check the deals for return flights from Santiago to Madrid in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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