Cheapest one-way flights from Santiago to Madrid in April from $531

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

29 Apr LATAM Airlines Group
28 Apr LATAM Airlines Group
07 Apr LATAM Airlines Group
03 Apr Aerolineas Argentinas
15 Apr LATAM Airlines Group
14 Apr LATAM Airlines Group
04 Apr LATAM Airlines Group
06 Apr Aerolineas Argentinas
23 Apr LATAM Airlines Group
27 Apr LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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