Cheapest one-way flights from Santiago to Madrid in April from $467

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

27 Apr LATAM Airlines Group
07 Apr LATAM Airlines Group
22 Apr LATAM Airlines Group
13 Apr LATAM Airlines Group
29 Apr LATAM Airlines Group
11 Apr LATAM Airlines Group
12 Apr Aerolineas Argentinas
15 Apr LATAM Airlines Group
06 Apr Avianca
04 Apr LATAM Airlines Group

Also check the deals for return flights from Santiago to Madrid in April.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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