Cheapest one-way flights from Santiago to Madrid in April from $488

AirHint found the following cheapest one-way flights from Santiago (SCL) to Madrid (MAD) in April 2026 (see full year).

One-Way flights

13 Apr Sky Airline
21 Apr Sky Airline
20 Apr Sky Airline
26 Apr LATAM Airlines Group
23 Apr LATAM Airlines Group
25 Apr LATAM Airlines Group
06 Apr LATAM Airlines Group
27 Apr Sky Airline
09 Apr LATAM Airlines Group
28 Apr Sky Airline

Also check the deals for return flights from Santiago to Madrid in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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