AirHint found the following cheapest one-way flights from Santiago (SCL) to Mendoza (MDZ) in October 2025 (see full year).

One-Way flights

14 Oct	Sky Airline	direct
27 Oct	Sky Airline	direct
26 Oct	Sky Airline	direct
22 Oct	Sky Airline	direct
03 Oct	Sky Airline	direct
16 Oct	Sky Airline	direct
23 Oct	Sky Airline	direct
21 Oct	Sky Airline	direct
11 Oct	Sky Airline	direct
10 Oct	Sky Airline	direct

Also check the deals for return flights from Santiago to Mendoza in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Santiago to Mendoza in October from $26

One-Way flights