Cheapest one-way flights from Santiago to Santa Cruz in December from $198

AirHint found the following cheapest one-way flights from Santiago (SCL) to Santa Cruz (VVI) in December 2025 (see full year).

One-Way flights

10 Dec LATAM Airlines Group
03 Dec LATAM Airlines Group direct
27 Dec JetSmart
06 Dec LATAM Airlines Group
02 Dec LATAM Airlines Group
30 Dec LATAM Airlines Group
24 Dec LATAM Airlines Group
17 Dec Sky Airline
01 Dec LATAM Airlines Group
22 Dec LATAM Airlines Group

Also check the deals for return flights from Santiago to Santa Cruz in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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