Cheapest one-way flights from Santiago to Madrid in October from $24

AirHint found the following cheapest one-way flights from Santiago (SCQ) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

25 Oct Iberia direct
03 Oct Iberia direct
04 Oct Iberia direct
27 Oct Iberia direct
15 Oct Ryanair direct
09 Oct Ryanair direct
16 Oct Ryanair direct
23 Oct Ryanair direct
01 Oct Iberia direct
14 Oct Iberia direct

Also check the deals for return flights from Santiago to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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