Cheapest one-way flights from Santiago to Madrid in September from $24

AirHint found the following cheapest one-way flights from Santiago (SCQ) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

02 Sep Ryanair direct
16 Sep Ryanair direct
09 Sep Ryanair direct
25 Sep Ryanair direct
17 Sep Ryanair direct
30 Sep Ryanair direct
05 Sep Ryanair direct
10 Sep Iberia direct
03 Sep Iberia direct
11 Sep Iberia direct

Also check the deals for return flights from Santiago to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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