Cheapest one-way flights from Santo Domingo to Sao Paulo in December from $285

AirHint found the following cheapest one-way flights from Santo Domingo (SDQ) to Sao Paulo (GRU) in December 2025 (see full year).

One-Way flights

04 Dec Frontier Airlines
13 Dec Arajet
14 Dec Frontier Airlines
16 Dec Copa
05 Dec Copa
18 Dec Copa

Also check the deals for return flights from Santo Domingo to Sao Paulo in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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