Cheapest one-way flights from Santander to Prague in December from $68

AirHint found the following cheapest one-way flights from Santander (SDR) to Prague (PRG) in December 2025 (see full year).

One-Way flights

15 Dec Vueling Airlines
16 Dec Vueling Airlines
18 Dec Vueling Airlines
23 Dec Ryanair
19 Dec Vueling Airlines
30 Dec Ryanair
17 Dec Vueling Airlines
05 Dec Vueling Airlines
06 Dec Ryanair
07 Dec Iberia

Also check the deals for return flights from Santander to Prague in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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