Cheapest one-way flights from San Francisco to Sao Paulo in December from $314

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Sao Paulo (GRU) in December 2025 (see full year).

One-Way flights

29 Dec Copa
13 Dec Frontier Airlines
15 Dec Frontier Airlines
23 Dec Sun Country Airlines
27 Dec Delta
22 Dec LATAM Airlines Group
19 Dec Frontier Airlines

Also check the deals for return flights from San Francisco to Sao Paulo in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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