Cheapest one-way flights from San Francisco to Madrid in September from $257

AirHint found the following cheapest one-way flights from San Francisco (SFO) to Madrid (MAD) in September 2025 (see full year).

One-Way flights

29 Sep TAP
28 Sep Iberia
25 Sep Frontier Airlines
23 Sep TAP
24 Sep TAP
24 Sep American Airlines direct
27 Sep Hawaiian Airlines
26 Sep Frontier Airlines
22 Sep Alaska Airlines
21 Sep Hawaiian Airlines

Also check the deals for return flights from San Francisco to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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