Cheapest one-way flights from Santa Ana to San Francisco in December from $49

AirHint found the following cheapest one-way flights from Santa Ana (SNA) to San Francisco (SFO) in December 2025 (see full year).

One-Way flights

16 Dec Alaska Airlines direct
13 Dec United direct
03 Dec Alaska Airlines direct
31 Dec Alaska Airlines direct
07 Dec Frontier Airlines direct
25 Dec Alaska Airlines direct
18 Dec Alaska Airlines direct
12 Dec Spirit Airlines
14 Dec Spirit Airlines
21 Dec Alaska Airlines direct

Also check the deals for return flights from Santa Ana to San Francisco in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in San Francisco

Cheap car rent in San Francisco

Feel free to contact us with any feedback or request another flight research.