AirHint found the following cheapest one-way flights from Split (SPU) to Rome (FCO) in September 2025 (see full year).

One-Way flights

30 Sep	Vueling Airlines	direct
23 Sep	Vueling Airlines	direct
27 Sep	Ryanair	direct
24 Sep	Vueling Airlines	direct
13 Sep	Ryanair	direct
15 Sep	Vueling Airlines	direct
17 Sep	Vueling Airlines	direct
28 Sep	Vueling Airlines	direct
11 Sep	Vueling Airlines	direct
09 Sep	Vueling Airlines	direct

Also check the deals for return flights from Split to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Split to Rome in September from $38

One-Way flights