AirHint found the following cheapest one-way flights from St. Louis (STL) to Cancun (CUN) in October 2025 (see full year).

One-Way flights

18 Oct	Spirit Airlines
25 Oct	Spirit Airlines
21 Oct	Frontier Airlines	direct
27 Oct	Frontier Airlines	direct
06 Oct	Frontier Airlines	direct
12 Oct	Frontier Airlines	direct
25 Oct	Volaris	direct
24 Oct	Frontier Airlines	direct
03 Oct	Frontier Airlines	direct
09 Oct	Frontier Airlines	direct

Also check the deals for return flights from St. Louis to Cancun in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from St. Louis to Cancun in October from $144

One-Way flights