Cheapest one-way flights from St. Louis to Detroit in September from $87

AirHint found the following cheapest one-way flights from St. Louis (STL) to Detroit (DTW) in September 2025 (see full year).

One-Way flights

12 Sep Frontier Airlines
21 Sep Frontier Airlines
29 Sep Frontier Airlines
29 Sep Southwest Airlines direct
15 Sep Frontier Airlines
05 Sep Frontier Airlines
07 Sep Frontier Airlines
04 Sep Frontier Airlines
21 Sep Delta direct
15 Sep Delta direct

Also check the deals for return flights from St. Louis to Detroit in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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