Cheapest one-way flights from St. Louis to Prague in November from $382

AirHint found the following cheapest one-way flights from St. Louis (STL) to Prague (PRG) in November 2025 (see full year).

One-Way flights

12 Nov Frontier Airlines
02 Nov Frontier Airlines

Also check the deals for return flights from St. Louis to Prague in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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