AirHint found the following cheapest one-way flights from Tenerife (TFN) to Santiago (SCQ) in December 2025 (see full year).

One-Way flights

15 Dec	Vueling Airlines	direct
16 Dec	Vueling Airlines	direct
17 Dec	Vueling Airlines	direct
13 Dec	Vueling Airlines	direct
11 Dec	Vueling Airlines	direct
14 Dec	Vueling Airlines	direct
10 Dec	Vueling Airlines	direct
12 Dec	Vueling Airlines
23 Dec	Vueling Airlines	direct
12 Dec	Vueling Airlines	direct

Also check the deals for return flights from Tenerife to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Tenerife to Santiago in December from $27

One-Way flights