AirHint found the following cheapest one-way flights from Tenerife (TFN) to Santiago (SCQ) in September 2025 (see full year).

One-Way flights

24 Sep	Vueling Airlines	direct
23 Sep	Vueling Airlines	direct
29 Sep	Vueling Airlines	direct
26 Sep	Vueling Airlines	direct
30 Sep	Vueling Airlines	direct
09 Sep	Vueling Airlines	direct
17 Sep	Vueling Airlines
15 Sep	Vueling Airlines
11 Sep	Vueling Airlines	direct
27 Sep	Vueling Airlines	direct

Also check the deals for return flights from Tenerife to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest one-way flights from Tenerife to Santiago in September from $27

One-Way flights