Cheapest one-way flights from Tampa to Panama City in December from $139

AirHint found the following cheapest one-way flights from Tampa (TPA) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

13 Dec American Airlines
01 Dec Copa direct
02 Dec Copa direct
05 Dec Copa direct
06 Dec Copa direct
07 Dec Copa direct
09 Dec Copa direct
10 Dec Copa direct
11 Dec Copa direct
12 Dec Copa direct

Also check the deals for return flights from Tampa to Panama City in December.

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