Cheapest one-way flights from Tampa to Santo Domingo in December from $132

AirHint found the following cheapest one-way flights from Tampa (TPA) to Santo Domingo (SDQ) in December 2025 (see full year).

One-Way flights

09 Dec Spirit Airlines
06 Dec Spirit Airlines
06 Dec Frontier Airlines direct
13 Dec Frontier Airlines direct
30 Dec Frontier Airlines direct
28 Dec Spirit Airlines
20 Dec Frontier Airlines
18 Dec Frontier Airlines direct
21 Dec Copa
21 Dec Frontier Airlines direct

Also check the deals for return flights from Tampa to Santo Domingo in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santo Domingo

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