Cheapest one-way flights from Santa Cruz to Madrid in December from $445

AirHint found the following cheapest one-way flights from Santa Cruz (VVI) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

25 Dec Air Europa direct
23 Dec Air Europa direct
04 Dec Air Europa direct
11 Dec Air Europa direct
02 Dec Air Europa direct
03 Dec GOL Linhas Aéreas
10 Dec GOL Linhas Aéreas
01 Dec Avianca
12 Dec GOL Linhas Aéreas
27 Dec Air Europa direct

Also check the deals for return flights from Santa Cruz to Madrid in December.

Powered by

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Feel free to contact us with any feedback or request another flight research.